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Stereotaxic technique Methods for studying cognitive behaviour (positive reinforcement - T-maze, radial 8-arm maze; negative reinforcement - shuttle box, step-through, step- down) Tests for measuring anxiety (elevated plus maze, Vogel's conflict test) Methods for studying exploratory and locomotor behaviour Experimental models of : - Parkinson's disease; - dementia; - epilepsy - depression (bilateral olfactory bulbectomy - OBX); Tests for measuring rat's responses to pain stimuli (paw pressure, tail flick, hot-plate, writhing test) Methods for studying seizure susceptibility (chemically and electricaly-induced seizures in mice and rats; kindling). Stereotaxic implantation of cannulae into different brain structures (intracerebral microinjections). Dissection of discrete brain areas Smart video tracking system (PanLab Harvars Apparatus, Holliston, USA) Experimental models of chronic temporal lobe epilepsy (kainate and pilocarpine - induced) Experimental model of depression (chronic unpredictable stress) Tests for measuring anxiety-like behavior (elevated plus-maze, Hole-board test Methods for studying motor activity and exploratory behavior (open field test), motor coordination ("Rota rod" test) Methods for studying emotional disturbance and depression (forced swimming test, sucrose consumption test) Tests for measuring rat's responses to nociceptive stimuli (paw pressure, hot-plate, writhing test; formaline test). Methods for acute and chronic physical restraint, immersional, cold and swimming stress, and oxidative stress: biochemical markers for oxidative stress Transcardial perfusion and dissection of discrete brain areas Methods for studying seizure susceptibility (chemically and electrically-induced seizures in mice and rats; kindling model of epilepsy) Stereotaxic implantation of cannulae into different brain structures (intracerebral microinjections)
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